hrp0097p1-482 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

Human milk short-chain fatty acids promote early myelination in a 2D human co-culture of oligodendrocytes and cortical neurons.

Elke Chie Stefanie , Szentpetery Zsofia , Natalucci Giancarlo , Consolata Miletta Maria

Background: Human milk is considered the most advantageous source of nourishment for infants. Although there is a growing body of evidence showing that human milk feeding fosters early neurodevelopment, the underlying process is still not completely known. Indeed, clinical and animal research has linked human milk to enhanced myelination in the infant's central nervous system, however, access to human oligodendrocytes and neurons in the early stages of develop...